Personally, I disagree because people will do dumb things with it and wonder why they can't get to their web interface to change it back.
I'm glad I stumbled on this thread and agree with ryecoaaron. I too desire the ability to specify/bind to a specific IP, but I totally understand that about .002% of users need to do this. And if you're one of the .002%, then we should be able to set the nginx config (and remember the setting in case it gets changed during an update).
What I'm trying to do, in this case, is use OMV a little like Unraid. I wanted to use Unraid, I paid for a license, and upon install suddenly realized it doesn't support group management? So sad! It has so many wonderful features when it comes to mergefs/snapraid like features, with a way to encrypt the drives in the UI. But I know I would have been disappointed along the way anyway considering that I've been using OMV for longer than I can remember and its plain linux with services on top. Every time I have a do it all GUI, something will frustrate the hell out of me.