But you won't be able to use your 'Pi Drive' with it (only as external drive). NanoPi NEO2 and Orange Pi Zero Plus are more or less the same. The only real difference is voltage regulation for the CPU. NEO2 is limited to 1.1V while OPi can switch between 1.1V and 1.3V which allows the latter to increase CPU clockspeeds up to 1.2 GHz (due to Dynamic voltage scaling depending on CPU Vcore voltage to reach higher clockspeeds).
Yes, the Pi Drive (along with the RPi itself) will probably become part of a Retropie gaming console. Thanks again for all the detailed information!