If your output doesn't look like this, it won't change. If your output does look like this, it will change with changes in the GUI
aaron@omv5dev:~$ ls -al /etc/resolv.conf
lrwxrwxrwx 1 root root 32 Jan 13 2020 /etc/resolv.conf -> /run/systemd/resolve/resolv.conf
is this true for OMV6 as well? the /etc/resolv.conf should be a symlink to the /run/systemd/resolve/ location?